by erica.westgate62. The Prefix "dis-" - YouTube. •I can spell a range of words which have the prefixes dis-, mis-, … Quiz. To not have as great of an advantage. Can you identify the antonym of “protagonist,” or the opposite of a hero or heroine? Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company. 1350–1400; Middle English