Passive immunity occurs when the antibodies (produced elsewhere) are administered; eg, the antibodies produced by a horse in response to snake venom is used in an emergency antivenin kit. The first and foremost difference between active immunity and passive immunity is that active immunity is being produced for the contact with pathogen or the antigen, whereas passive immunity is being produced for the antibodies that are obtained from outside. When you are immune to a disease, your immune system can fight off infection from it. Another distinctive difference between active immunity and passive immunity is that active immunity lasts for an adequately long period and even might be life long, whereas passive immunity lasts for at least a few days. In the active immunity system pathogen has a direct contact with the body while in passive immunity the pathogen does not have any direct contact with the body of the person. This kind of immunity could take place naturally, for example when a newborn baby is receiving the antibodies from his or her mother by breast milk or placenta; or it could even occur artificially, for example when any specific person is receiving these antibodies within the form of an injection like gamma globulin injections. There are some of the major and the most significant and important differences between active immunity and passive immunity. The immunity that is being derived from the passive immunization majorly lasts for only a few weeks to almost 3 to 4 months/ There also exists a major threat for the hypersensitivity reactions such as gamma reactions. The antigen is like an organism's ID. The vaccine of hepatitis A comprises a specific license from the late 1980s, with the scope that there are follow up studies for protection duration, getting restricted to lesser than twenty-five years. Comparison Table Between Active and Passive Immunity (in Tabular Form) What is Active Immunity? Passive Immunity Active immunity is the type of adaptive immunity that comes in direct contact with the pathogens, antigens or the foreign harmful elements, whereas passive immunity is the type of adaptive immunity that does not need to be in direct contact with the bacteria, pathogen or any other harmful foreign elements. Start studying active and passive immunity. Thus, there could a preceding caveat regarding the time period for protection from the viral or bacterial attacks. Differences between Active Immunity and Passive Immunity. The artificially acquired passive immunity is even being utilized during the treatment of various acute infections as well as treating poison effects. This can be natural or artificial/induced. 3. Required fields are marked *. We acquire passive immunity by receiving antibodies that were not made by our own bodies. The entire process of active immunity system is extremely easy to understand. Immunity can be gained actively or passively. This artificially acquired passive immunity majorly gives immediate protection, however, human bodies never develop memory and thus the respective patient resides at basic risk to get infected by the same pathogen unless and until they need proper vaccination or active immunity for the person. In this article, we compare and contrast two types of acquired immunity: active and passive immunity. On the other hand, passive immunity is when an individual receives lymphocytes and antibodies produced from the immune system of another individual. For human beings, MatAb or maternal antibody is being passed on through placenta to infant or foetus through the receptor of FcRn over the cells of placenta. The antibodies are being passed from the mother’s body to her infant even before he or she is born and hence conferring a passive immunity system to the infant during the 1st four to six months. Active immunity is majorly classified as either acquired immunity or natural immunity. Active immunity commonly involves your body direct response to unknown pathogen. Immunity is defined as the body’s ability to protect itself from an infectious disease. It led to a life long protection of the respective body. This specific response is the result of antibodies which is specific to antigen of pathogen. Active immunity system does not give a rapid response while on the other hand passive community provides a rapid response. Passive immunity occurs naturally when maternal antibodies are moved to fetus through placenta. Hence, it is being often reduced in infants, who have a premature birth. Active immunity is produced actively by host’s immune system as a result of the stimulation by antigen. Difference between Herd Immunity and Passive Immunity Meaning – Herd immunity describes a state of immunity acquired when a significant fraction of the population develops resistance to an infection for some reason other than prior exposure or immunization, and which breaks the chain of subsequent spread of the infection. 1. In spite of this fact, the maternal IgG could eventually inhibit a proper induction of the protective vaccine response in the entire first year. Active immunity takes place when the host produces antibodies when exposed to pathogens or bacteria while passive immunity takes place when the host receives antibodies from another source. The maternal passive immunity can be referred to as the kind of naturally acquired passive immunity, which subsequently refers to an antibody-mediated immunity conveyed to the foetus by the respective mother. In the case of passive immunity, protection is immediate. Difference Between Active And Passive Immunity is that The immune system protects the body from a variety of pathogens and toxins. Innate immunity is even termed as genetic or natural immunity. Innate immunity provides first-line defense against pathogens through physical and chemical barriers such as skin, mucous layers, and saliva. The fourth difference between these two immunities is that the antibodies are being produced by the human body as per response to the antigen or pathogen, whereas in passive immunity, these distinctive antibodies are being gained from the inside body. The antibodies developed from the active immunity are highly specific to that serotype or serovar, but the passive immunity based antibodies are not that specific because of its external origin and prone to early destruction due to this external origin. Passive immunity is where antibodies and lymphocytes are produced by another individual immune system. Passive immunity occurs when antibodies produced artificially are injected into a person to counteract antigens such as snake venom, rabies, tetanus toxin and Salmonella infection. The other differences include: 1. Both active and passive immunity can be natural or artificial. Your email address will not be published. All rights reserved. In active immunity greater time is required as immunity needs to be developed through a certain process while in passive immunity no such process is required as immunoglobbin are directly injected. Now before we proceed, let us define some terms Let us define the term antigen first. The following are some of the major differences between active and passive immunity. Active immunity indicates the formation of antibodies through direct exposure to an antigen. This type of immunity majorly refers to the procedure to expose a body to the antigen for the core purpose of generating an adaptive response for immune, which could take up days or weeks for development, however, it might not be extremely long-lasting. This type of immunity can be divided into two types, which are external and internal. The main difference between active and passive immunity is that active immunity is developed by the production of antibodies by person’s own body whereas passive immunity is developed by the antibodies which are produced outside. The fifth important or vital difference between active immunity and passive immunity is that in active immunity, there are extremely fewer side effects, however, in passive immunity, the human body eventually reacts to antisera initiation, which is termed as serum sickness. Let's take a closer look at active and passive immunity and the differences between them. Pediatricians can protect your child by administering not only active immunizations, but sometimes they can use what physicians call passive immunizations.If you hear your pediatrician use these terms, this is what they mean. The immunization is also needed shortly after the following birth only for preventing diseases within the newborn babies like pertussis, polio, hepatitis B and tuberculosis. The present post discusses the Similarities and Differences between the Active and Passive Immune Systems with a Comparison Table. Active immunity is that immunity system which occurs because of the production of antibodies by the natural process of person’s own immune system in response to an antigen while on the other hand Passive immunity is that immunity which results from the antibodies from the outside world. So, for example the natural form of passive immunity is antibodies transferred in breast milk as mentioned, however an artificial form of passive immunity is the use of antidotes such as that for rabies where specific antibodies are injected into an infected individual. It eventually helps in the successful reduction of symptoms for diseases include immune suppression. This can be done through breast milk or via an infusion. Simply submit your order and see what our writers can Subscribe to get regular update! When the antibodies to antigens are produced by our own bodies, we call it active immunity. There are two types of passive immunity, which are natural immunity and artificial immunity. Weakened pathogens can no longer cause serious illness. Click here to Signup, Already have an account? Active immunization occurs naturally in response when antigen is received by the person who does not come into contact with microbe and does not have any antibodies for defense.